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研究队伍

宋海燕 副研究员,硕士研究生导师

主要研究领域:中医药防治慢性肝病的临床基础研究。

主要研究方向:肝炎、肝癌病理机制及中医药防治的药效和药理机制。

近几年代表性研究成果:

论文:

1. Xu H, Wang L, Zheng P, Liu Y, Zhang C, Jiang K, Song H*, Ji G*. Elevated serum A20 is associated with severity of chronic hepatitis B and A20 inhibits NF-κB-mediated inflammatory response. Oncotarget. 2017 Jun 13;8(24):38914-38926. doi: 10.18632/oncotarget.17153. PMID:28473659

2. Shijun Hao, Chunlei Zhang, Haiyan Song*, Natural Products Improving Hyperuricemia with Hepatorenal Dual Effects, Evidence-Based Complementary and Alternative Medicine, 2016, 2016: 1-7, DOI:10.1155/2016/7390504

3. Haiyan Song#, Jielu Pan#, Yang Liu, Hongzhu Wen, Lei Wang, Jiefeng Cui, Yinkun Liu, Bing Hu, ZeminYao, Guang Ji*, Increased ARPP-19 expression is associated with hepatocellular carcinoma, International Journal of Molecular Sciences, 2015, 16(1): 178-192

4. Yang Liu#, Haiyan Song#, Lei Wang, Hanchen Xu, Xiangbing Shu, Li Zhang, Ying Li, Dongfei Li, Guang Ji*, Hepatoprotective and antioxidant activities of extracts from Salvia-Nelumbinis naturalis against nonalcoholic steatohepatitis induced by methionine- and choline-deficient diet in mice, Journal of Translational Medicine, 2014, 12(315): 1-10

5. Rongxin Chen#, Haiyan Song#, Yinying Dong, Chao Hu, Qiongdan Zheng, Tongchun Xue, Xiaohui Liu, Yang Zhang, Jie Chen, Zhenggang Ren, Yinkun Liu, Jiefeng Cui*, Dynamic expression patterns of differential proteins during early invasion of hepatocellular carcinoma, PLos One, 2014, 9(3): 1-9

6. Lei Wang#, Li Zhang#, Xiaoxia Feng, Lianjun Xing, Wei Zhang, Kaiping Jiang, Haiyan Song*, Guang Ji*, The functional difference of dendritic Cells in HBeAg negative chronic hepatitis B patients with three different spleen deficiency syndromes and the therapeutic evaluation of Chinese medicine intervention based on syndrome differentiation, Evidence-Based Complementary and Alternative Medicine, 2014, 2014:1-10

7. Haiyan Song#, Li Zhang, Jielu Pan, Lili Yang, Guang Ji*, Bioactivity of five components of Chinese herbal formula Jiangzhi granules against hepatocellular steatosis, Journal of Integrative Medicine, 2013, 11(4): 262-268

8. Haiyan Song#, Zhimin Mao, Lili Yang, Tao Liu, Dongfei Li, Li Zhang, Yingli Ge, Peiyong Zheng, Ping Liu, Xiaoqi Zhang, Guang Ji*, Dangfei Liganning Capsules attenuate the susceptibility of rat nonalcoholic fatty liver to carbon tetrachloride toxicity, Journal of Traditional Chinese Medicine, 2011, 31(4): 327-333

9. Nicolas Moniaux#, Haiyan Song, Marion Darnaud, Kevin Garbin, Michelle Gigou, Claudia Mitchell, Didier Samuel, Laure Jamot, Paul Amouyal, Gilles Amouyal, Christian Brechot, Jamila Faivre*, Human hepatocarcinoma-intestine- pancreas/pancreatitis-associated protein cures fas-induced acute liver failure in mice by attenuating free-radical damage in injured livers, Hepatology, 2011, 53(2): 618-627

10. 崔恬冰,邢练军,季光,宋海燕*. 三叶因子3在消化系统疾病中的作用. 中国新药与临床杂志中医学, 2018.5, 37(5): 249-254

11. 周岐鸣,刘洋,季光,宋海燕*. 调节自噬改善非酒精性脂肪性肝病的药物研究进展. 中华中医药学刊, 2018.10, 36   (10): 2463-2467

12. 宋海燕#,刘洋,毛志敏,徐汉辰,杨丽丽,柳涛,季光*,当飞利肝宁胶囊预防非酒精性脂肪性肝病大鼠肝纤维化,中西医结合肝病杂志,2013233):154-156, 187

13. 宋海燕#,毛志敏,杨丽丽,张莉,葛迎利,柳涛,刘平,季光*,当飞利肝宁胶囊改善高脂饮食联合四氯化碳诱导的大鼠非酒精性脂肪性肝炎的作用机制,临床肝胆病杂志,2012283):196-200

 参编著作:

1. 《非酒精性脂肪性肝病的中医药治疗》北京. 20161月,科学出版社(编委)


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