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研究队伍

袁建业  研究员硕士研究生导师

主要研究领域:中医药防治脾胃(消化)病的临床基础研究。

主要研究方向:肠易激综合征的病理生理机制及中药防治肠易激综合征的药效物质基础和药理机制。

近几年代表性研究成果:

论文:

1. Sun B#, Yuan J# (co-first author), Wang S, Lin J, Zhang W, Shao J, Wang R, Shi B and Hu H* (2018) Qingchang Suppository Ameliorates Colonic Vascular Permeability in Dextran-Sulfate-Sodium-Induced Colitis. Front. Pharmacol. 9:1235. doi: 10.3389/fphar.2018.01235IF3.831

2. Yinshu Wang, Zijuan Bi, Enkang Wang, Boyun Sun, Yu Zheng, Linda LD Zhong*, Jianye Yuan*. Rodent model of irritable bowel syndrome. International Journal of Gastroenterology Disorders and Therapy, 2017; 4: 131

3. Zijuan Bi, Yu Zheng, Jianye Yuan*, Zhaoxiang Bian*. The Efficacy and Potential Mechanisms of Chinese Herbal Medicine on Irritable Bowel Syndrome. Current Pharmaceutical Design, 2017; 34(23): 5163-5172IF2.611

4. 毕紫娟, 张仕晟, 袁建业*. 益生菌与肠易激综合征. 医学综述, 2017; 23(1): 125-130,133

5. Jianye Yuan, Wensheng Liu, Serhan Karvar, Susan S. Baker, Wenjun He, Robert D. Baker, Guang Ji, Jianqun Xie, Lixin Zhu*. Potassium channel KCNJ15 is required for histamine-stimulated gastric acid secretion. Am J Physiol Cell Physiol, 2015; 309: C264-70 IF3.78

6. Hai-Lian Shi#,,, Chu-Hsuan Liu#,, Li-Li Ding, Yu Zheng, Xiao-Yan Fei, Lu Lu, Xue-Ming Zhou, Jian-Ye Yuan* and Jian-Qun Xie. Alterations in serotonin, transient receptor potential channels and protease-activated receptors in rats with irritable bowel syndrome attenuated by Shugan decoction. World Journal of Gastroenterology, 2015; 21(16): 4852-4863IF2.369

7. 陈瑶, 郑昱, 石海莲, 费晓燕, 袁建业*. 糖尿病胃排空异常与ghrelin的关系. 世界华人消化杂志, 2014; 22(34): 5298-5303

8. Jianye Yuan, Susan S. Baker, Wensheng Liu, Razan Alkhouri, Robert D. Baker, Jianqun Xie, Guang Ji, and Lixin Zhu*. Endotoxemia unrequired in the pathogenesis of pediatric nonalcoholic steatohepatitis. Journal of Gastroenterology and Hepatology, 2014; 29(6): 1292-1298 IF3.627

9. 袁建业, 尚静娟, 谢建群*, 郑昱, 费晓燕, 石海莲, 孙巧丽. 疏肝饮对避水应激大鼠内脏痛觉过敏的调节作用. 中华中医药学刊, 2012; 30(10): 2190-2192

10. JianYe Yuan, JiYan Zhou, ZhiBi Hu, Guang Ji, JianQun Xie, DaZheng Wu. The effects of jatrorrhizine on contractile responses of rat ileum. European Journal of Pharmacology, 2011; 663(1-3): 74-79IF2.737

参编著作:

1. Chinese Internal Medicine》北京.20139月,人民卫生出版社(编委)

2. 《中西医结合临床研究方法学》北京.201612月,人民卫生出版社(编委兼学术秘书)

3. 《糖尿病名家妙方+饮食》北京.201610月,化学工业出版社(共同主编)


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