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研究队伍

顾明 研究实习员

主要研究领域:中医药防治代谢性疾病药理研究。

主要方向:小分子通过核受体治疗代谢性疾病的药理研究。

近几年代表性研究成果:

论文:

1. Gu M, Zhang Y, Liu C, et al. Morin, a novel liver X receptor α/β dual antagonist, has potent therapeutic efficacy for nonalcoholic fatty liver diseases. Br J Pharmacol. doi: 10.1111/bph.13933 (2017). (IF:6.81)

2.  Gu M, Zhang S,Zhao Y, et al. Cycloastragenol improves hepatic steatosis by    activating farnesoid X receptor signalling. Pharmacol Res. doi: 10.1016/j.phrs.2017.04.021 (2017). (IF:4.89)

3. Ming Gu, Ping Zhao, Jinwen Huang, et al. Silymarin Ameliorates Metabolic Dysfunction Associated with Diet-Induced Obesity via Activation of Farnesyl X Receptor. Front. Pharmacol. Sep 28;7:345 (2016). (IF:4.41)

4. Ming Gu, Yu Zhang, Shengjie Fan, et al. Extracts of Rhizoma Polygonati Odorati Prevent High-Fat Diet-Induced Metabolic Disorders in C57BL/6 Mice. PLoS One. 29;8(11):e81724. doi: 10.1371 (2013). (IF:.3.53)

5. Ming Gu, Shengjie Fan, et al. Extract of wax gourd peel (EWGP) prevents high-fat diet-induced hyperlipidemia in C57BL/6 mice via the inhibition of the PPARγ pathway. Evid-Based Compl Alt Med. doi: 10.1155/2013/342561 (2012). (IF: 2.06)

6.顾明;黄诚*. 《减肥药研发:窘境背后的希望》.中国新药杂志. (2013).


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